Clinical Trials Xpress (CTX) is an initiative of the University of Texas System established to provide an efficient and scalable centralized operating model for conducting multi-site clinical trials. Envisioned by the Texas Regional Clinical and Translational Science Award (CTSA) Consortium (TRCC), this collaboration brings together premier academic institutions, physician investigators and experienced research professionals under a shared vision to accelerate the pace of clinical trials from concept to completion.
To leverage UT resources, shared informatics tools and operational best practices and rapidly identify sites and physician investigators for fast-track implementation of multi-site clinical trials.
CTX and its central coordinating office is dedicated to providing investigators and industry sponsors a single point-of-entry to access streamlined processes and a dedicated team to coordinate the efficient launch of multi-site clinical trials. Together with support from institution-based CTX Navigators and Research Administration teams, the CTX model disrupts traditional bottlenecks to substantially simplify study start-up.
Collaborative Clinical Research Solutions, Inc. was retained by UT System to establish the infrastructure and provide experienced, dedicated staffing to manage the day-to-day operations of the CTX Network. Together with the TRCC and its working groups,the CTX Central Operations staff has rapidly defined organizational structures, processes and standard operating procedures necessary to launch Clinical Trials Xpress.
CTX was envisioned by the Texas Regional CTSA Consortium (TRCC), a UT System-wide consortium of NIH-funded Clinical and Translational Science Award (CTSA) programs.
The founding CTSA award institutions include UT Health and MD Anderson Cancer Center in Houston, UT Medical Branch in Galveston, UT Southwestern Medical Center in Dallas and UT Health in San Antonio. The CTX Network infrastructure allows for expansion to other UT and non-UT institutions to participate in the CTX portfolio of clinical trials. Additional hospitals, community-based clinics and disease-specific networks are expected to be added to this roster.
The TRCC Executive Committee sets the criteria for the selection and prioritization of the CTX clinical trial portfolio. TRCC working groups, with trans-campus representation, help to define the CTX processes and criteria for site selection, credentialing, initiation, training and staff education.
CTX has made meaningful strides by leveraging available resources of UT trans-campus working groups and TRCC executive leadership, who bring deep subject matter expertise in the areas of clinical trials research administration, subject recruitment, data management, bioinformatics, specimen procurement and banking, and research best practices.